I can easily prove in no uncertain terms that ANY antidepressant will raise serotonin levels high enough to block an Ecstasy trip.
There are a couple reasons why an antidepressant will crank you up much higher than Ecstasy without (totally) tripping you out and without killing you, even though the end result is harder on your emotional neurons and will kill them faster than a full time Ecstasy high, and it’s easy to prove.
Ecstasy (MDMA) functions by causing your brain to suddenly release it’s entire reserve of serotonin at once. And people who have dropped Ecstasy and then go on antidepressants, and THEN drop Ecstasy, can’t feel the ecstasy.
The reason is simple – your brain only has a certain number of serotonin receptors, and after a while on an antidepressant, which blocks the reuptake of serotonin, your synapses become so over saturated with serotonin that it occupies all receptor sites, so having more be suddenly released by a hit of Ecstasy produces no perceivable effect.
If you read the druggie blogs, they often complain about Ecstasy no longer working once they start taking antidepressants.And Ecstasy is well known to be a burn out drug, that causes permanent damage very quickly with repeated use. In fact, there have been many studies that say ONE Ecstasy high for a single night can permanently change people’s emotional condition, for life. Some people get serious damage from a single use.
Since Ecstasy is not an officially approved drug, the bad stories are easy to find. Interesting it is that the approved drug – the one your doctor recommends, is far worse than what any street junkie would throw your way. Since an antidepressant puts the serotonin levels higher than Ecstasy will, and keep them that high indefinitely, the damage is usually severe and permanent.
Ahh, but there is a question here - Ecstasy produces a very noticeable high, and very noticeable warped perception, and does this by simply boosting serotonin levels. Since you trip out on Ecstasy, and you don’t usually trip out on an antidepressant, that means Ecstasy is worse, right? well, NO.
There is a reason why an antidepressant does not usually produce Ecstasy like hallucinations, and it’s easy to explain.
When you take a hit of Ecstasy, your serotonin levels go from normal to max in a few minutes. This puts the brain off balance, with no time to adjust to the difference. The neurons are fresh and not over worked, so they output a lot of sensation. This causes the Ecstasy “trip”.
When you take an antidepressant, it takes several weeks for the serotonin to build up to the level of an Ecstasy high. And ANY druggie will tell you that if you want to blow your entire stash, don’t do it all at once. Do it a step at a time, and let yourself settle down a bit before the next hit, because if you take too many hits at ONE TIME, you will be likely to overload and overdose. You can get much higher without overdosing or totally flipping out by slowly toking yourself up. And that’s exactly how an antidepressant does it.
No meth high, cocaine high, Ecstasy high, pot high, heroin high, or whatever other high lasts more than a couple days, then you crash. And druggies can toke themselves up REALLY high over the course of a day.
With an antidepressant, the high is intended to last until you are destroyed. That means it never backs off. That means you continuously get higher and higher and higher until you clip out, and can’t get any higher. This makes a mega high drug, like Ecstasy, have little or no effect. You don’t know you are THAT high, because it took weeks to get there. It takes a long time for the brain to naturally release THAT MUCH serotonin, so since the releases of serotonin are always at a natural pace while using an antidepressant, and only build upon previous releases that happened at a natural pace, you don’t trip out (usually), you just get really cheery after a while.
And the junkies who complain about not being able to get high on Ecstasy while doing antidepressants are PERFECT PROOF.
In a study done on rats which were fed either prozac, (fluoxitine) or zoloft, the rats exhibited the exact same brain damage as what happens with ecstacy use. A group of rats were fed prozac for only four days, while another was fed Ecstasy. Both groups then had their brains dissected. In both groups, the axons (the connection at the end of a dendrite that forms the receiving side of a synapse) were severely swollen, and took on a corkscrew shape. It was obvious that the corkscrewed axons would no longer function normally. And that was after only four days. Rats are considered to be a suitable test for what will happen in people.
The prozac damage was exactly the same as a heavy Ecstasy regimen, where the high was continued for the same period of time. Such Ecstasy highs are seldom done, because everyone knows that if you crank yourself up for a week on Ecstasy without stopping, your emotions are likely to be permanently wrecked. Why no warnings about Prozac?
And nowadays, prozac (fluoxetine) is the mild one they give to children. WTF is up with that?
When you put the facts on the table, it is OBVIOUS that antidepressants are ONE THING, and ONE THING ONLY. AN ACT OF WAR AGAINST THE SOUL ITSELF. It could take dying to get it back. Take a look at this poor chap trying to get off of Effexor, and read the comments below!