The next video is not going to be popular with many, but I would submit the fact that mafia hit-men long preferred .22s for their assassinations. A big part of that was, admittedly, because of the comparatively lesser noise report of that ammunition and the obviously unwanted attention attracted by a louder firearm; but, it was also because the .22 caliber round is known to bounce-around inside people’s skulls, making minced-meat out of their brains. It can be very lethal with either proper shot-placement and/or multiple shots. A .22 in a home invader’s leg probably isn’t gonna save your life, but 7 of them in the guy’s chest probably will. A shotgun is still the best home defense gun, in my opinion, but some folks aren’t physically-capable of firing a shotgun or a high-caliber handgun, so we need to look at other possibilities.
A bit of bad language in some of the videos below, so beware.