Researchers find new risk factor for two mental illness disorders in Ashkenazi genes

rabbiThe Ugly Truth

Israeli, American researchers publish work on new genetic risk factor for schizophrenia, bipolar disorder. The grounds of the Hebrew University of Jerusalem.

jpost.com

Israeli and American researchers investigating a healthy Ashkenazi Jewish population have identified a new genetic risk factor for schizophrenia and bipolar disorder (manic-depression).  

Their work, just published in Nature Communications, was reported by scientists at the Feinstein Institute for Medical Research in Manhasset, New York and at the Hebrew University of Jerusalem.

The researchers identified the defect in the gene, named NDST3, by studying more than 25,000 individuals.

Conducting the study was a team led by Dr. Todd Lencz at the Zucker Hillside Hospital’s department of psychiatry research and the Feinstein Institute, and HU’s Dr. Ariel Darvasi, who has studied Ashkenazi populations for disorders for many years.

Lencz has been working with a set of DNA samples from patients with schizophrenia and healthy volunteers from the Ashkenazi population, which has inbred for many centuries.

Ashkenazim represent a unique population for study because of their relatively short (less than 1,000-year) history and limited population. This history results in a more uniform genetic background in which to identify diseaserelated variants.

“This study again demonstrates the value of our Ashkenazi cohort,” said Lencz. “It is notable that the genetic variant was replicated in samples of various ethnicities from all around the world, but the effects were strongest in the Ashkenazi cohort, presumably due to their unique genetic history.”

Lencz’s team reported that the genetic variant, which changes a single “letter” of the DNA code, alters the expression of the gene NDST3. This gene is critical to neurodevelopmental processes such as axon formation and synaptic function.

These findings shed new light on the genetic architecture and potential therapeutic targets for the treatment of psychiatric disease.

Schizophrenia and bipolar disorder are severe psychiatric disorders that affect 1 percent to 4% of the global population.

Studies have shown that the two disorders are likely to have a large overlap in genetic risk factors, but only a small portion of this genetic risk has been identified.

A grant from the US National Institute of Mental Health supported this work.

More recently, Lencz’s and Darvasi’s work on Ashkenazim received an additional $3 million from the NIMH, as well as grants from the Brain and Behavior Foundation and the Binational Science Foundation.

http://theuglytruth.wordpress.com/2014/01/14/researchers-find-new-risk-factor-for-two-mental-illness-disorders-in-ashkenazi-genes/

13 thoughts on “Researchers find new risk factor for two mental illness disorders in Ashkenazi genes

    1. More accurately- this is likely part of the curse with which they were plagued with after having turned Jesus over to pilot. they said let the blood of him be on our children, and children’s children. i would go insane too if i realized i crucified my Messiah.

      1. If and only if the Ashkenazim are Israelites, which (if Koestler and various Israeli geneticists are right) they are not. Koestler says they are Khazars 9and he is one of them…read “The Thirteenth Tribe”). Schlomo Sand and others have already said the Palestinians are more likely to be related to Christ (being Semites and all) than Ashkenazim, who are not even Semites, but Japhethites (Ashkenaz was son of Gomer, son of Japheth)

        1. Very likely descended from the Pharisees, who were descended from the Canaanites, and the Edomites (Esau), who were Israel’s mortal enemy.

  1. In history how many countries have they been ejected from? Why?

    Oh Gee Wiz. How many Christian East Europeans have they mass murdered in the 20th century? Over 60,000,000 just in Russia alone. Not even counting Poland, Hungary, Chekaslovakia, Romania, Yugoslavia, etc…

    Now they control everything in USA. Why do we put up with these crazy genocidal freaks of nature? We’re Americans. Why are we standing and taking all their crap!!!! They’ve already destroyed California. Whos next?

    1. Jfk move to have israel listed as a hostile foreign entity and look what happened shortly thereafter. this infestation of the faux-jew into all position of power has been a multi-generational plan brought about by luciferic tendency. our tenacity along with supernatural help from the Creator is the only thing that will deliver us from this evil. the evil must be allowed to occur for a time for there to be evidence of their evil intent during the final judgment. we must however never stop fighting the evil, for evil triumphs when good men/women do nothing about it.

  2. There are 112 genetic/hereditary jewish diseases and an inordinate
    percentage of insanity in this race. Syphilis originated in the jewish
    race d/t their unclean habits and tainted the entire lineage and has
    carried through to today through genetic inbreeding. Hence, the
    term “dirty jew”; and circumcision which was an attempt to stop the
    spread of syphilis within the tribe. They are attempting to impose
    their unclean sexual perversions on the rest of the world. General
    Patton recognized them for what they are.

    1. Awe Leita, I got to say it, Ya think they swallow when doing their oral circumcision thing. Wouldn`t suprise me if they did. 😉

  3. So Steven Segall is a “dirty jew”. He sure looks like he has a bad case of syphilis in the photo at the top of the article.

  4. I wonder who they will railroad to extort reparations from? Hopefully there weren’t another “6 million” holocausted. First zyklon B,now syphillis

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